IWK Drug Information Resource
Note: This provides a rough estimate for converting IV FentaNYL to PO morphine. There is significant individual response to
various opioids as well as unpredictable or incomplete tolerance between opioids; clinical judgement must always be used when converting opioids.
Neonates can be more susceptible to adverse effects of opioids therefore consider starting at a lower dose than what the conversion suggests.
Please note: the calculated PO morphine dosing is an approximate conversion; consider a decrease or increase in recommended dose depending on the patient’s clinical status.
Consider the following prior to implementation: